You NEVER know how it will affect you until you do it, that is, you can NOT apply statistics (population) to your case (individual), and mull what Dr. Peter Hackett (Institute For Altitude Medicine founder) opines on AMS.Consider the risk/reward of each method.
Actual Susceptibility --> Will be affected -- Won't be affected
Acclimatize for days: helps avoid sickness -- waste of hiking days (vacation time)
Hike a 14er w/o delay: turn back pre-summit -- successful summit
The results for "acclimatizing" are avoiding a negative (non-negative, not the same as positive, zero is non-negative) or negative, and interference to point/goal of the trip.
The results for "hike w/o delay" are a various (from negative if you continue to ascend despite early signs, to positive in getting some hiking in before turning around at first signs) to positive, and also achieving the point/goal of the trip.
Wager the only one that yields a positive option and hike on your first day in Colorado. Go hike but pay attention to your body, and if need be, turn around and descend. Up to you how long you want to "acclimatize" (hike next day, one break day, two break days, ...) if that's what your body (not someone else's body) tells you.
Besides, you've already been up ten 14ers already!
